| 陈云龙 陈文峰 林阿丰 钱剑英 黄冬梅.慢性荨麻疹患者外周血T淋巴细胞检测的意义[J].实用中西医结合临床,2012,(1):4-5 |
| 慢性荨麻疹患者外周血T淋巴细胞检测的意义 |
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| DOI： |
| 中文关键词: 慢性荨麻疹 T淋巴细胞 疗效观察 |
| 英文关键词: T-lymphocyte subgroup Chronic urticaria Clinical observation |
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| 中文摘要: |
| 目的：探讨慢性荨麻疹患者外周血T淋巴细胞水平变化的意义。方法：分别检测并比较正常人群与慢性荨麻疹患者外周血CD3+、CD3+CD4+、CD3+CD8+、CD3+CD4+/ CD3+CD8+等指标水平情况；检测并比较慢性荨麻疹患者治疗前后治愈组、显效组、进步组及无效组外周血CD3+、CD3+CD4+、CD3+CD8+、CD3+CD4+/ CD3+CD8+等指标水平变化情况。结果：慢性荨麻疹患者外周血CD3+、CD3+CD4+等指标明显低于正常组；CD3+CD8+、CD3+CD4+/ CD3+CD8+与正常组无明显差异。治疗前后外周血CD3+、CD3+CD4+等指标水平明显变化，且CD3+、CD3+CD4+指标变化情况与疗效成正相关关系。结论：外周血T淋巴细胞可以作为观察临床疗效的有效指标。 |
| 英文摘要: |
| Objective:To observe the influence of T-lymphocyte subgroup in patients with chronic urticaria.Methods： Divide all the case into two groups ： group one was normal group，the other was patient’s group.T-lymphocyte subgroup(including CD3+、CD3+CD4+、CD3+CD8+ and the ratio of CD3+CD4+/ CD3+CD8+) was measured between two groups and conpared before and after treatment in patient’s group.Results：CD3+ and CD3+CD4+ in patient’s group were lower than normal group , and there were significant difference between two groups（P <0.05）, while there were no significant difference in CD3+CD8+、the ratio of CD3+CD4+/ CD3+CD8+（P >0.05）. In patient’s group : CD3+、CD3+CD4+ were significant difference between before and after treatment , and can be negative correlation with curative effect.Conclusion：T-lymphocyte subgroup in patients with chronic urticaria might play an important role in clinical observation. |
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