CD44v6 和 MMP9在子宫内膜癌中表达的研究

付秋风; 熊勇; 孙丽萍; 秦贇娜; 于晓红

文章摘要

付秋风熊勇孙丽萍秦贇娜于晓红.CD44v6 和 MMP9在子宫内膜癌中表达的研究[J].实用中西医结合临床,2010,(6):70-72

CD44v6 和 MMP9在子宫内膜癌中表达的研究

DOI：

中文关键词: CD44v6 MMP9 子宫内膜癌免疫组织化学

英文关键词: CD44v6 MMP9 Immunohistochemcal methocl Endometrial carcinoma

基金项目:

作者	单位
付秋风熊勇孙丽萍秦贇娜于晓红	江西省妇幼保健院

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中文摘要:

目的：探讨CD44v6、 MMP9在子宫内膜癌中表达的意义。方法：采用免疫组织化学Elivision Plus法对78例子宫内膜癌中CD44v6和MMP9表达进行检测及分析。结果：CD44v6和MMP9的表达与子宫内膜癌病理分级、临床分期无关，与淋巴结转移有关。结论：CD44v6、 MMP9在淋巴结转移过程中起着重要作用，有助于早期预测转移潜能，判断预后及指导术后干预治疗。

英文摘要:

Objective:To detect the expression of CD44v6 and MMP9 protein in endometrial carcinoma．Methods:The expression of CD44v6 and MMP9 were detected by immunohistochemical method in 78 cases of endometrial carcinoma.Results:The expression of CD44v6 and MMP9 were neither correlated with pathological grading nor clinical stages; its expression was up-expressed in the case of lymph node metastasis.Conclusion:CD44v6 and MMP9 playing the important roles in the lymph node metastasis ,it could help to predict the metastasis potentidlity on the early phase,estimate the prognosis and direct the interference therapy after operation.

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