文章摘要
王荣国.加味四君子汤联合拉米夫定治疗慢性乙型肝炎疗效观察[J].实用中西医结合临床,2010,(5):11-12
加味四君子汤联合拉米夫定治疗慢性乙型肝炎疗效观察
  
DOI:
中文关键词: 慢性乙型肝炎  加味四君子汤  拉米夫定  对照研究
英文关键词: Chronic hepatitis B  Jiawei Sijunzi decoction  Lamivudine  Controlled study
基金项目:
作者单位
王荣国 广东省佛山市顺德区容奇医院 
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中文摘要:
      目的:观察加味四君子汤联合拉米夫定治疗慢性乙型肝炎的疗效。方法:治疗组采用加味四君子汤联合拉米夫定治疗,拉米夫定每天1次,每次100mg;加味四君子汤每天2次,每次150mL,每周连续服用6d,暂停1d,疗程1年。对照组单用拉米夫定100mg,每天1次,疗程1年。结果:治疗组总有效率为90.0%,对照组为70.0%,两组比较有显著性意义;治疗组在HBeAg转阴、HBV-DNA转阴及ALT、AST、TBil复常等方面均优于对照组。结论:加味四君子汤联合拉米夫定治疗慢性乙型肝炎可提高疗效,起协同作用。
英文摘要:
      Objective:To explore the therapeutic effects of patients with Chronic hepatitis B (CHB) treated by Jiawei Sijunzi decoction and lamivudine. Methods: The treatment group was treated by Jiawei Sijunzi decoction and lamivudine for one year. Jiawei Sijunzi decoction 150mL,twice one day, in consecutive six days a week, suspension one day. lamivudine 100mg,once a day. The control group was treated only by lamivudine 100mg,once a day for one year. Results: The total effective rates were 90.0% in the treatment group and 70.0% in the control group. Significant difference was found between the two groups. The rations of recovery for liver functions (ALT、AST、TBil), the sero-conversion rate of HBV-DNA and HBeAg seroconversion rates in the treatment group were better than in the control group. Conclusion: Jiawei Sijunzi decoction which play synergies can improve the efficacy of lamivudine in CHB cases.
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