| 张绪平 石磊 刘朝晖.单发与多发乳腺纤维腺瘤中雌激素受体的表达差异及意义[J].实用中西医结合临床,2009,(6):66-67 |
| 单发与多发乳腺纤维腺瘤中雌激素受体的表达差异及意义 |
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| DOI： |
| 中文关键词: 乳腺纤维腺瘤 雌激素受体 阳性率 复发 |
| 英文关键词: Breast fibroadenoma Estrogen receptor Positive expression rate Recrudescent |
| 基金项目: |
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| 中文摘要: |
| 目的：检测雌激素受体（ER）在单发与多发（肿瘤个数≥2个）乳腺纤维腺瘤中的表达，观察单发与多发乳腺纤维腺瘤复发率的差异。方法：80例单发与80例多发乳腺纤维腺瘤光镜下回顾性观察，并对肿瘤组织进行ER免疫组织化学染色。结果：ER在单发纤维腺瘤与多发纤维腺瘤中的表达阳性率分别为61.2%和77.5%，P <0.05。术后3年，80例多发乳腺纤维腺瘤有19例复发，而80例单发者3例复发，P <0.05。结论：多发纤维腺瘤的ER表达阳性率大于单发者，多发纤维腺瘤的复发率大于单发者。 |
| 英文摘要: |
| Objective:To detect the expressions of estrogen receptor(ER) in single and multiple breast fibroadenoma tissue and observe the differences of the recrudescence rate between single and multiple fibroadenoma tissue.Methods: Observation of eighty cases of single breast fibroadenoma and eighty cases of multiple breast fibroadenoma retrospectively under the light microscope, and performance of immunohistochemical staining for ER in tumor tissues. Result: Positive expression rates for ER in single and multiple fibroadenoma tissue are 61% and 78%,P <0.05.3 years after operation, there are 19 cases recrudescent in eighty cases of multiple fibroadenoma.and 3 cases recrudescent in eighty cases of single fibroadenoma,P <0.05.Conclusion:The ER-positive rate of multiple fibroadenoma is higher than single persons. The recrudescence rate of multiple fibroadenoma is higher than single persons. |
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