鲁努.中重度高血压治疗中缬沙坦与双氢克尿噻联合用药的研究[J].实用中西医结合临床,2009,(4):88-89 |
中重度高血压治疗中缬沙坦与双氢克尿噻联合用药的研究 |
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DOI: |
中文关键词: 中重度高血压 缬沙坦 双氢克尿噻 |
英文关键词: Valsartan Hydrochlorothiazide Moderate and severe hypertension |
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中文摘要: |
目的:观察缬沙坦与双氢克尿噻联合降压的疗效及安全性。方法:选取中、重度高血压患者78例,全部符合WHO/ISH高血压诊断标准。用缬沙坦80mg,1次/d,加双氢克尿噻12.5mg,1次/d,观察8周。结果:中、重度高血压患者的降压总有效率分别为96.0%、92.8%,而且患者血清电解质、血脂、血糖和心肾功能治疗前后无明显差异。结论:缬沙坦与双氢克尿噻联用降压效果显著,且对患者血清电解质、血脂、血糖和心肾功能影响小。 |
英文摘要: |
Objective:Observe the security and effect of valsartan combined with hydrochlorothiazide to blood pressure. Method:78 patients, accord with the diagnose standard of WHO/ISH hypertension.80mg valsartan qd,combined with 12.5mg hydrochlorothiazide qd,observed for 8 week. Result: The effective to blood pressure for moderate and severe hypertension were 96.0% and 92.8%.And there’s no different in serum liquid blood glucose, cardiac and renal function before and after therapy. Conclusions: It has remarkable effect for valsartan combined with hydrochlorothiazide and with low influence to patients’ serum liquid ,blood glucose, cardiac and renal function. |
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