| 王留记.芪苈强心胶囊联合曲美他嗪治疗慢性充血性心力衰竭临床观察[J].实用中西医结合临床,2008,(5):5-6 |
| 芪苈强心胶囊联合曲美他嗪治疗慢性充血性心力衰竭临床观察 |
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| DOI： |
| 中文关键词: 芪苈强心胶囊 曲美他嗪 慢性充血性心力衰竭 |
| 英文关键词: Qiliqiangxin capsule Trimetazidine Chronic contractive heont failure |
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| 中文摘要: |
| 目的：观察芪苈强心胶囊联合西药治疗中、重度慢性充血性心力衰竭（CHF）的疗效及安全性。方法：将80例CHF患者随机分为两组，对照组给予ACEI类、利尿剂、小剂量地戈辛片和酒石酸美托洛尔片，治疗组在对照组治疗基础上加服芪苈强心胶囊（4粒/次，每日3次）、曲美他嗪片（20mg/次，每日3次），4周时比较两组治疗效果。结果：治疗组心功能改善率、总有效率、左室射血分数（LEVF）提高率分别为：97.5% 、100% 、（30±5）%，而对照组分别为87.5% 、92.5% 、（13±4）% ，两组比较差异有统计学意义（P <0.05或P <0.01），治疗组生活质量改善优于对照组(P <0.01)，两组均未发现明显不良反应。结论：芪苈强心胶囊合用曲美他嗪及其他西药治疗CHF具有明显疗效和良好的安全性。 |
| 英文摘要: |
| Objective:To observe the therapeutic effect of Qiliqiangxin capsule combined with western medicine on moderate and severe chronic contrative heart faicure(CHF).Methods:40 patients with CHF in control group were treated with ACEI uretica small dose of beta-blocker tablet and digoxin .the 40 patients in treatment group on the basis of control group,were treated by Qiliqiangxin capsule four pills once three times a day and trimetazidine 20mg once three times a day,the therapeatic effects were observed and compared after four-weeks treatment in the two groups.Results:The total effective rate of cardiac function improvement,total effective rate of improvement of TCM symptoms and increasing rate of left ventricle ejection fraction (LVEF)in treatment group were 97.5%,100%,(30±5)% respectively,but which in control group were 87.5%,92.5%,(15±4)%,there was a significant difference between the two groups (P <0.05 or P <0.01),the side effects were not found in both groups.Conclusion:In the treatment of moderate and severe chronic contractive heart failure,Qiliqiangxin capsule combined with western medicine could improve cardiac function effectively,alleviate clinical symptoms and increase LVEF with safety. |
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