| 王铭 张瑞麟 刘娜 候晋.血脂康治疗中医不同证型高脂血症的临床疗效观察[J].实用中西医结合临床,2008,(2):1-2 |
| 血脂康治疗中医不同证型高脂血症的临床疗效观察 |
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| DOI： |
| 中文关键词: 血脂康 辨证分型 高脂血症 疗效差异 |
| 英文关键词: Xuezhikang Syndrome classification by differentiation Hyperlipemia Different therapeutical effect |
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| 中文摘要: |
| 目的：研究血脂康治疗中医不同证型高脂血症的临床疗效差异。方法：选择300例高脂血症患者，根据中医辨证分型分为五组，运用血脂康进行降脂治疗，治疗前后观察血脂指标和中医证候积分的变化。结果：经8周降脂治疗后与治疗前比较，各组血清低密度脂蛋白含量均明显降低(P <0.01，P <0.05)，其中痰浊阻遏组和气滞血瘀组疗效明显优于其它三组（P <0.05）。痰浊阻遏组较治疗前总胆固醇/高密度脂蛋白（TC/HDL）比值下降最为明显（P <0.01），且明显优于其它各组（P <0.05）；气滞血瘀组、阴虚阳亢组、肝肾阴虚组该比值下降具有显著性（P <0.05）；脾肾阳虚组治疗前后该比值无差异（P＞0.05）。痰浊阻遏组、阴虚阳亢组和气滞血瘀组中医证候积分明显下降(P <0.01，P <0.05)，其余两组差异不明显（P＞0.05），痰浊阻遏组明显优于其它四组(P<0.05)。结论：血脂康降脂治疗能够显著降低血脂水平，但存在证型疗效差异，其中痰浊阻遏组综合疗效较好，而脾肾阳虚组疗效则最不明显。 |
| 英文摘要: |
| Objective:To study the different therapeutical effect of Xuezhikang Capsule on treating different TCM syndrome types.Methods:300 patients with hyperlipemia are divided into five groups according to the differentiation types of TCM. All patients are given Xuezhikang Capsule. The course of treatment is 8 weeks. Changes of index of blood fat and TCM syndrome integral are observed after treatment. Results:After 8 weeks, the LDL of all groups has obviously lowed(P <0.01，P <0.05), and the groups of sputum stasis syndrome and qi-stagnation induced blood-stasis syndrome are lower than the three others（P <0.05）. The TC/HDL of sputum stasis syndrome group has lowed mostly（P <0.01）and gains an advantage on other groups（P<0.05）; the TC/HDL of qi-stagnation induced blood-stasis, yin-deficiency and yang-excessive and hepatic and renal yin deficiency syndrome group has significantly lowed（P <0.05）; and the Spleen-Yang Deficiency and Kidney-Yang Deficiency syndrome group has no significance. The TCM syndrome integral of sputum stasis , yin-deficiency and yang-excessive, and qi-stagnation induced blood-stasis syndrome group has lowed obviously(P <0.01，P <0.05), the two other groups has no significance（P ＞0.05）,and the sputum stasis syndrome groups gains an advantage on the four others(P <0.05).Conclusive:The Xuezhikang capsule can reduce the level of blood fat, but the differentiation of syndrome types has existed, and the sputum stasis syndrome type has good effect, then the he Spleen-Yang Deficiency and Kidney-Yang Deficiency syndrome type has no significance. |
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