| 杨康治 吴少华 陈正珊 项素素 冯思国.更昔洛韦联合西米替丁治疗婴幼儿轮状病毒肠炎疗效观察[J].实用中西医结合临床,2008,(1):13-14 |
| 更昔洛韦联合西米替丁治疗婴幼儿轮状病毒肠炎疗效观察 |
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| DOI： |
| 中文关键词: 轮状病毒肠炎 更昔洛韦 西米替丁 婴幼儿 |
| 英文关键词: Rotavirus enteritis Ganciclovir Cimetidine Infant |
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| 中文摘要: |
| 目的：探讨更昔洛韦联合西米替丁治疗婴幼儿轮状病毒肠炎的疗效。方法：将112例轮状病毒性肠炎患儿随机分为更昔洛韦组、更昔洛韦+西米替丁组和对照组三组。结果：治疗72h总有效率对照组、更昔洛韦组、更昔洛韦+西米替丁组分别为57.5%、87.5%、90.0%,更昔洛韦组、更昔洛韦+西米替丁组明显高于对照组(P <0.05或P <0.01);更昔洛韦+西米替丁组总有效率与更昔洛韦组比较差异无显著性意义(P >0.05)，但显效率明显高于更昔洛韦组 (P <0.05)。结论：更昔洛韦与西米替丁联合治疗婴幼儿轮状病毒肠炎疗效较好，值得临床应用。 |
| 英文摘要: |
| Objective: To explore the effect of ganciclovir and cimetidine therapy on infants with rotavirus enteritis.Methods:112 infants with rotavirus enteritis were randomly divided into ganciclovir group，ganciclovir+cimetidine group and control group. Results: The total effective rates of control group， ganciclovir group and ganciclovir+cimetidine group in first 72 hours of the treatment were 57.5%，87.5% and 90.0%. The total effective rates of ganciclovir group，ganciclovir+cimetidine group were significantly higher than that of control group(P <0.05&P <0.01).There was no significant difference between ganciclovir+cimetidine group and ganciclovir group(P > 0.05)，but the notable effective rates of the former group were significantly higher than that of ganciclovir group(P <0.05).Conclusion: Ganciclovir and cimetidine in treating infants with rotavirus enteritis is effective. |
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