| 赵香珍 周俊俊 范惠英.生殖道衣原体感染与宫颈上皮内瘤样病变[J].实用中西医结合临床,2007,(6):14-15 |
| 生殖道衣原体感染与宫颈上皮内瘤样病变 |
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| DOI： |
| 中文关键词: 沙眼衣原体 解脲支原体 宫颈上皮内瘤样病变 |
| 英文关键词: Chlamydia trachomatis Ureaplasma urealyticum Cervical Intraepithelial neoplasia |
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| 中文摘要: |
| 目的：探讨沙眼衣原体及解脲支原体感染与宫颈上皮内瘤样病变（CIN）发病机制的关系。方法：采用聚合酶链反应法对161例CIN患者和78例正常对照者的宫颈分泌物进行沙眼衣原体及解脲支原体DNA检测。结果：161例CIN宫颈分泌物检测沙眼衣原体感染率明显升高，与对照组相比差异显著（P <0.05）；沙眼衣原体及解脲支原体混合感染率升高，与对照组相比差异显著（P <0.05）；而解脲支原体感染2组差异无显著性（P >0.05）；CIN各级感染率无明显差异。结论：沙眼衣原体感染与CIN的发生可能密切相关。 |
| 英文摘要: |
| Objective:To evaluate the relationships between chlamydia trachomatis(CT) or ureaplasma urealyticum(UU) infection and cervical intraepithelial neoplasia(CIN).Methods:Immunochromatographic method and direct culture was used to examine the CT and UU in cervical secretion in 161 CIN group and 78 normal control group.Results:54 of 161 CIN patients with CT DNA positive.The CIN group of CT infected had a significantly higher rate than that of the control group (P <0.05).The co-infection of two in CIN group also had a higher rate than that of control group(P <0.05).But UU infection had no significant difference between the three CIN group and the normal control group (P >0.05).Conclusion:CT infection maybe play a important role in the pathogenesis of CIN. |
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