| 张雪峰 张文军 金仲达.肾活检68例临床与病理分析[J].实用中西医结合临床,2007,(5):33-34 |
| 肾活检68例临床与病理分析 |
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| DOI： |
| 中文关键词: 肾活检 临床表现 病理分型 |
| 英文关键词: Renal biopsy Retrospective analysis Pathological classification |
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| 中文摘要: |
| 目的：回顾性分析本科自1998年12月~2005年12月共68例因肾脏疾病行活检的病理资料，总结常熟地区肾脏疾病的临床病理类型特点。 方法：参照WHO肾小球疾病组织学分型修订方案(1982年及1995年)，对每1例患者均进行临床病理讨论，由病理医师和临床医师结合临床资料、实验室检查结果、免疫病理及超微结构改变特点，共同探讨明确病理诊断及拟定相应的治疗措施。 结果： 本组中原发性肾小球疾病占92.65%，继发性肾小球疾病占7.35%。原发性肾小球疾病以系膜增生性肾炎（MsPGN）居多(32.35%),其次分别为局灶节段增生性肾小球肾炎（FSGP）(26.47%)、微小病变（MCD）(19.12%)、膜性肾病（MN）（8.82％）、FSGS(5.88%)等。继发性肾脏病中以狼疮性肾炎（LN）多见(4.41%),其次是紫癜性肾炎（HSPN）(1.47%)等。临床表现为肾病综合征患者，以MN多见（31.25%），其次为MsPGN（25.0%）、FSGS(12.5%)等。临床表现为尿检异常患者，以MsPGN多见（40.0%），其次为FSGP(32.5%)、MCD(17.5%)、FSGS(5.0%)等。 结论： 常熟地区原发性肾小球肾炎仍是最常见的肾小球疾病,其中以系膜增生性肾小球肾炎和微小病变最常见, 继发性肾脏病以狼疮性肾炎多见,女性占绝对优势。肾活检的适应证可以扩大。 |
| 英文摘要: |
| Objective:From 1998 to 2005,68 cases of percutaneous renal biopsy were performed in Changshu district. The pathologic entities were analyzed retrospectively and the clinical pathological characteristics of renal diseases in Changshu district were concluded. Methods: Pathological classifications were made according to the WHO criteria of 1982 for renal pathology or the modified WHO criteria of 1995 by apanel of pathologists and nephrologists sinroutine clinic alpathological rounds. The rapymeasures were also made by the panel. Results:Primary glomerular diseases(PGD)accounted for 92.65% of the total renal biopsies, second aryglome rulonephritis (SGN) 7.35%. Mesangial proliferative glomerulonephritis (MsPGN) was the most frequent patholigical type (32.35%) of PGD, followed by focal segmental glomerulonephritis (FSGP) (26.47%),minimal change disease (MCD) (19.12%),membra-nous nephropathy (MN) (8.82%), focal segmental glomerulosclerosis (FSGS) (5.88%).The most frequent type of SGN was lupusnephritis (LN) (4.41%),followed by purpuric glomerulonephritis (HSPN) (1.47%). MN was the most frequent patholigical type(31.25%) of nephritic syndrome (NS), followed by MsPGN (25.0%),FSGS (12.5%) ,et al. MsPGN was the most frequent patholigical type (40.0%) of urine abnormal (Uab), followed by FSGP (32.5%),MCD (17.5%), et al.Conclusion: In Changshu district, MsPGN is still the most frequent pathological type in primary glomerular diseases. In SGN ,LN is the most frequent and female patients are still predominant. The indications are enlarged. |
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