| 刘东 李成香.充血性心力衰竭患者血浆脑钠素及肌钙蛋白T水平的变化[J].实用中西医结合临床,2007,(5):3-4 |
| 充血性心力衰竭患者血浆脑钠素及肌钙蛋白T水平的变化 |
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| DOI： |
| 中文关键词: 心力衰竭 充血性 脑钠素 肌钙蛋白T |
| 英文关键词: Congestive heart failure Brain natriuretic piptide Cardiac Tropnin T |
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| 中文摘要: |
| 目的：探讨血浆脑钠素、血清肌钙蛋白T( cTnT)水平的变化在充血性心力衰竭患者中的临床意义。方法：分别采用免疫放射法(IRMA)及Roche公司生产的Elecsys Systems 2010全自动电化学发光免疫分析系统测定40例充血性心力衰竭患者及20例同期非心血管病者（对照组）的血浆脑钠素、血清肌钙蛋白T水平。结果：心力衰竭患者组血浆脑钠素、血清cTnT测定值明显高于正常对照组(P <0.01) ；重度心衰(心功能Ⅳ级)组的血浆脑钠素、血清cTnT测定值及异常检出率显著高于中度心衰(心功能Ⅲ级)组 (P <0.01)；中度心衰组血浆脑钠素、血清cTnT测定值及异常检出率明显高于轻度心衰(心功能Ⅱ级)组(P <0.01)。结论：血浆脑钠素、血清肌钙蛋白T在充血性心力衰竭患者中明显升高，且升高程度与病情的严重性相一致,提示其在心衰的发生发展中发挥重要作用。 |
| 英文摘要: |
| Objective:To study the clinic significance of plasma brain natriuretic piptide(BNP) and cardiac tropnin T content in patients with congestive heart failure(CHF).Methods: The 40 patients with different degree of congestive heart failure and 20 patients with non - heart disease ( the control group) were measured ，The plasma BNP content was measured by radioimmunnoassy and The plasma cTnT content was measured by Roche Eleccys systems 2010.Results:The plasma BNP and cTnT content was significantly higher in CHF than in control group(P <0.05),Along with increase in severity of heart failure,the plasma BNP and cTnT content increased significantly(P <0.01).Conclusion:The plasma BNP and cTnT content was significantly high in CHF, It is suggest that BNP and cTnT may play an impatant role in the developent of CHF. |
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