文章摘要
张焯文.肾康饮对小儿急性肾小球肾炎的治疗作用[J].实用中西医结合临床,2007,(2):38-39
肾康饮对小儿急性肾小球肾炎的治疗作用
  
DOI:
中文关键词: 小儿  急性肾小球肾炎  肾康饮  中西医结合疗法
英文关键词: Acute glomerulonephritis  Shenkang oral liquid  Integrated traditional Chinese and western medicine therapy  children
基金项目:
作者单位
张焯文 遵义医学院第五附属珠海医院 
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中文摘要:
      目的:观察肾康饮治疗小儿急性肾小球肾炎的临床疗效。方法:将112例住院及门诊急性肾小球肾炎患儿随机分2组,对照组给予西医常规治疗,如使用抗生素(青霉素或红霉素)、利尿剂(双氢克尿噻)及降血压药等对症治疗,并注意卧床休息及低钠盐饮食等;治疗组在西医常规治疗的基础上加服自拟肾康饮(由茯苓、泽泻、茅根、蝼蛄、鳖甲、肾炎草、生大黄等组成),每日1剂,水煎2次后混匀分次口服,连用2周为1个疗程。观察2组患者用药前后24h尿蛋白定量、1h尿红细胞排泄率、血尿素氮(BUN)、血清肌酐(SCr)及临床疗效。结果:肾康饮能显著减轻急性肾小球肾炎患者24h尿蛋白定量[由(223±114)mg/24h降到(107±51)mg/24h,P <0.01]及1h尿红细胞排泄率[由(32±6)×104/h降到(12±5)×104/h,P < 0.01],且使用过程中无不良反应。结论:在常规治疗的基础上加服自拟肾康饮,可以阻止急性肾小球肾炎小儿患者蛋白尿及血尿的迁延,显著改善临床症状。
英文摘要:
      Objective: To observe therapeutic effect of Shenkang oral liquid in treatment of acute glomerulonephritis(AGN). Methods: 112 children with AGN were randomly divided into the control group (n=56) and treatment group (n=56).Children in control group were treated with antibiotic (penicillin or erythromycin), patients accompanied edema and hypertension symptom were treated to symptom. Children in treatment group were treated with Shenkang oral liquid on the base of treatment of control group. The course in two groups were all two weeks. 24 hours urine protein quantity, 1 hour urine red blood cell excreting rate, blood urea nitrogen and serum creatinine before and after the treatment were observed. Results: Shenkang oral liquid could markedly lighten 24 hours urine protein quantity [reduced from (223±114)mg/24h to (107±51)mg/24h P <0.01] and significantly reduced 1 hour urine red blood cell excreting rate [reduced from (32±6)×104/h to (12±5)×104/h P <0.01]. There was no side effect in the course of using Shenkang oral liquid. Conclusion: Shenkang oral liquid could treat AGN and improve its symptom.
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