王秋华 王鹤 暴党振 黄一宁.通心络胶囊治疗脑梗死20例在64排CT灌注上的比较分析[J].实用中西医结合临床,2007,(2):12-13 |
通心络胶囊治疗脑梗死20例在64排CT灌注上的比较分析 |
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DOI: |
中文关键词: 脑梗死 通心络胶囊 CT灌注 |
英文关键词: Cerebral infarction Tongxinluo capsule 64 slice CT perfusion |
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中文摘要: |
目的:通过对通心络胶囊治疗脑梗死20例在64排CT灌注结果的分析,以验证其在治疗缺血性脑血管病方面的效果。方法:40例发病时间小于24h的急性缺血性脑血管病患者随机分成2组。治疗组20例在常规治疗基础上加服通心络胶囊2~4 粒, 每日3 次,用药3周为1个疗程; 对照组的20例仅常规治疗。2组脑血管病患者治疗前、后分别做64排CT灌注成像检查并进行比较。治疗组和对照组患者治疗前后血流灌注异常区域面积自身对比应用配对样本T检验。1个疗程的治疗后,对照组与治疗组血流灌注异常区域变化程度的比较,应用独立样本T检验进行评价。结果:2组治疗前后血流灌注异常区域面积自身比较均有显著性差异(P <0.05)。治疗组与对照组比较后显示,第二次灌注显示比第一次灌注成像时显示的血流灌注异常区域减小显著,P <0.05, XT>XC。结论:通过CT灌注成像、后处理图像上面积大小的比较,说明通心络胶囊在改善梗死区脑组织(缺血半暗带)的供血、促进梗死区周边神经细胞的生长与修复、增强神经细胞代偿功能、防止血栓形成等方面确有显著疗效。 |
英文摘要: |
Objective:To evaluate the effect of Tongxinluo capsule on Cerebral infarction. Methods:40 patients with cerebral infarction were randomly allocated to two groups. In treatment group (n =20) Tongxinluo capsule (4 pills ,three times per day )combined with routine therapy was administered with a therapeutic course of 3 weeks. In contrast group (n = 20) with routine therapy was administered. Result:There is significant difference between areas with abnormal perfusion before and after treatment (P <0.05). 3 weeks after the treatment, decreased abnormal perfusion areas of the treatment group are more significant than those of the contrast group(P < 0.05), XT>XC. Conclusions:The observation suggested that Tongxinluo capsule treat effectively Cerebral infarction. |
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