黄冠成.肝硬化并发严重感染患者C反应蛋白、前降钙素测定的临床意义[J].实用中西医结合临床,2006,(4):3-,10 |
肝硬化并发严重感染患者C反应蛋白、前降钙素测定的临床意义 |
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DOI: |
中文关键词: 前降钙素 肝硬化 细菌感染 C反应蛋白 |
英文关键词: Procalcitonin Serum C-reactive protein Hepatocirrhosis Infecion |
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中文摘要: |
目的:分析肝硬化并发严重感染时血清前降钙素、C反应蛋白的变化及其临床意义。方法:对25例肝硬化并发自发性细菌性腹膜炎和败血症的患者,测定其血清和腹水的前降钙素(PCT)和反应蛋白(CRP)。结果:合并严重感染时,PCT明显增高,增高幅度与感染程度呈正比,且与未合并感染者的差异有显著性(P <0.05);同时还发现PCT的增高与CRP的升高呈正相关。结论:PCT是诊断肝硬化并发严重感染的一个新型、敏感的实验室指标,对于鉴别感染与否,是否为细菌性感染具有较好的特异性。 |
英文摘要: |
Objective:To analyse the levels of serum C-reactive protein(CRP) and procalcitonin(PCT) in hepatocirrhosis patients with severe infection. Methods:Sera from 28 hepatocirrhosis patients with spontaneous bacterial peritonitis and septicemia were assayed for detection of PCT and CRP. Results:PCT level elevated in severe infection patients,and there was significant difference in PCT between infection patients and non-infection patients(P =0.00).PCT was positively related with CRP. Conclusion:PCT is a new sensitive indicator for diagnosis of severe bacterial infection,and has good specificity for distinguish bacterial from non-bacterial infection. |
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