李先辉 高辉 程传国 周永芹.高频水针疗法对颈椎病神经根性痛患者外周血TNF-α含量
及中性粒细胞百分率影响的初步研究[J].实用中西医结合临床,2006,(4):1-3 |
高频水针疗法对颈椎病神经根性痛患者外周血TNF-α含量
及中性粒细胞百分率影响的初步研究 |
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DOI: |
中文关键词: 颈椎病神经根型 肿瘤坏死因子 高频水针疗法 相关性 中性粒细胞 |
英文关键词: cervical spondylotic radiculopathy TNF-α High Frequency Hydro-acupuncture Relativity PMNs |
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中文摘要: |
目的:研究TNF-?琢、中性粒细胞(PMNs)与神经根型颈椎病(CRS)根性痛的相关性及高频水针疗法对该病患者血清TNF-?琢含量、PMNs百分率的影响。方法:收集20例符合条件的CRS患者,按门诊就诊顺序随机分为观察组和对照组,各10例,观察组用高频水针疗法,对照组用水针疗法。同时与20例正常人作对照。于治疗前和1个疗程后清晨空腹抽取静脉血, ELISA法检测血清TNF-?琢含量及行血常规检查。结果: TNF-?琢含量升高且与根性痛程度成正相关(r=0.830,P <0.01),PMNs百分率虽然升高,但与根性痛程度无相关性(r=0.210,P>0.05)。高频水针组和水针组均能改善患者的TNF-α含量、PMNs百分率,但前者对TNF-?琢含量、PMNs百分率的改善情况好于后者(P <0.01)。结论: TNF-?琢与神经根型颈椎病根性痛程度成正相关。高频水针疗法能降低或抑制炎性细胞因子的释放,具有明显的抗炎、镇痛作用,对神经根性痛有明显的干预作用。 |
英文摘要: |
Objective:To study the relativity between TNF-?琢 and PMNs with nerve-root pain of cervical spondylotic radiculopathy (CSR) and the effect of High Frequency Hydro-acupuncture(HFA) therapy on peripheral blood TNF-?琢 content and PMNs with CSR. Methods:20 cases were randomly divided into the observation group (10cases) and the control group (10cases).The observation group was treated with HFA and the control group was treated with Hydro-acupuncture(HA).We collected their peripheral blood sample as comparing as the normal group.The content of TNF-?琢 was measured by ELISA. Results:In patients with CSR, The content of TNF-?琢 were higher than the normal control and associated with the degree of pain (r=0.830,P <0.01),the percentage of polymorphonuclear leukocytes (PMNs) were higher than the normal control but not associated with degree of pain (r=0.210,P >0.05).The HFA and the HA can all improve the content of TNF-α,but the degree that the former improves the content of TNF-?琢 is better than the latter.Conclusion:Our study suggested that there is positive correlation between TNF-?琢 and CRS with nerve-root pain.The HFA can reduce or inhibit the release of inflammatory cytokines,and have the obviously function to inhibit inflammation and to alleviate pain,and have the obviously interfure function to nerve-root pain.. |
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