| 林寿宁 黄贵华 王振常.壮肝逐瘀煎对肝纤维化大鼠血清学的影响[J].实用中西医结合临床,2004,(1):1-3 |
| 壮肝逐瘀煎对肝纤维化大鼠血清学的影响 |
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| DOI： |
| 中文关键词: 壮肝逐瘀煎 肝纤维化 血清学 动物模型 |
| 英文关键词: Zhuang Gan Zhu Yu Jian Liver fibrosis serum markers Animal model |
| 基金项目:广西壮族自治区自然科学基金资助项目（NO：桂科0229047） |
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| 摘要点击次数: 891 |
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| 中文摘要: |
| 目的：通过大鼠肝纤维化动物模型，研究壮肝逐瘀煎防治肝纤维化的作用效果及其机理。方法：采用四氯化碳（CCL4）复合因素大鼠肝纤维化模型，予壮肝逐瘀煎灌胃，观察其对肝纤四项及形态学的影响，以大黄蟅虫丸为对照。结果：壮肝逐瘀煎显著降低大鼠血清中HA、LN、IV-C、PC-III的水平，并能减轻肝脏炎症及纤维化程度。结论：壮肝逐瘀煎具有抗肝纤维化作用。 |
| 英文摘要: |
| Objective:To investigate the effect and mechanisim of ZhuangGanZhuYuJian in treatment of liver fibrosis in rat model.Methods:After making the model with Carbon tetrachloride combined factors and treated with ZhuangGanZhuYuJian.The indexes of hepatofibrosis and pathology of liver were observed,using DaHuangZheChongWan as control.Results:The serum level of HA、LN、IV-C and PC-III were significantly decreased,and the formation of liver fibrosis was successfully ameliorated by the ZhuangGanZhuYuJian.Conclusion:ZhuangGanZhuYuJian could retain the progression of liver fibrosis. |
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