| 赵荣，张鼎，刘艳，王珊，袁岳鹏，张鸣波.黄芪桂枝五物汤联合温针灸治疗糖尿病周围神经病变（气虚血瘀证）的临床研究[J].实用中西医结合临床,2022,22(3):5-9,34 |
| 黄芪桂枝五物汤联合温针灸治疗糖尿病周围神经病变（气虚血瘀证）的临床研究 |
| 目的：探究经方黄芪桂枝五物汤联合温针灸治疗糖尿病周围神经病变（气虚血瘀证）的临床疗效及对患者神经传导速度的影响。方法：将80例患者随机分为观察组和对照组，每组40例。在采用相同基本治疗及健康宣教的基础上，对照组给予单用甲钴胺片治疗，观察组在对照组基础上加用黄芪桂枝五物汤联合温针灸治疗。两组疗程均为8周。观察两组治疗前后多伦多神经症状评分系统（TCSS）评分、神经电生理检查结果、中医症状积分，临床疗效及不良反应发生情况。结果：两组治疗后TCSS评分较治疗前明显降低，且观察组明显低于对照组（P＜0.05）；两组治疗后神经传导速度较治疗前明显提高，且观察组明显高于对照组（P＜0.05）；两组治疗后中医症状积分较治疗前明显降低，且观察组明显低于对照组（P＜0.05）；观察组治疗总有效率为95.0%，明显高于对照组的87.5%，差异具有统计学意义（P＜0.05）；两组治疗过程中均未发生明显不良反应。结论：在常规治疗及甲钴胺治疗的基础上采用黄芪桂枝五物汤联合温针灸治疗糖尿病周围神经病变（气虚血瘀证）患者，能够明显改善患者临床症状及体征，有利于神经功能恢复，延缓疾病进展，临床疗效确切且安全性较高。 |
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| DOI： |
| 中文关键词: 糖尿病周围神经病变 黄芪桂枝五物汤 温针灸 气虚血瘀证 甲钴胺 神经电生理 |
| 英文关键词: Diabetic peripheral neuropathy Huangqiguizhiwuwu decoction Warming needle moxibustion Qi deficiency and blood stasis syndrome Mecobalamin Neuroelectrophysiology |
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| 中文摘要: |
| 目的：探究经方黄芪桂枝五物汤联合温针灸治疗糖尿病周围神经病变（气虚血瘀证）的临床疗效及对患者神经传导速度的影响。方法：将80例患者随机分为观察组和对照组，每组40例。在采用相同基本治疗及健康宣教的基础上，对照组给予单用甲钴胺片治疗，观察组在对照组基础上加用黄芪桂枝五物汤联合温针灸治疗。两组疗程均为8周。观察两组治疗前后多伦多神经症状评分系统（TCSS）评分、神经电生理检查结果、中医症状积分，临床疗效及不良反应发生情况。结果：两组治疗后TCSS评分较治疗前明显降低，且观察组明显低于对照组（P＜0.05）；两组治疗后神经传导速度较治疗前明显提高，且观察组明显高于对照组（P＜0.05）；两组治疗后中医症状积分较治疗前明显降低，且观察组明显低于对照组（P＜0.05）；观察组治疗总有效率为95.0%，明显高于对照组的87.5%，差异具有统计学意义（P＜0.05）；两组治疗过程中均未发生明显不良反应。结论：在常规治疗及甲钴胺治疗的基础上采用黄芪桂枝五物汤联合温针灸治疗糖尿病周围神经病变（气虚血瘀证）患者，能够明显改善患者临床症状及体征，有利于神经功能恢复，延缓疾病进展，临床疗效确切且安全性较高。 |
| 英文摘要: |
| Objective: To explore the clinical efficacy of Huangqiguizhiwuwu decoction combined with warming needle moxibustion in treating diabetic peripheral neuropathy (Qi deficiency and blood stasis syndrome) and its effect on nerve conduction velocity of patients. Methods: 80 Eligible patients were randomly divided into observation group and control group, with 40 cases in each group. On the basis of the same basic treatment and health education, the control group was given mecobalamin tablets alone, and the observation group was treated with Huangqiguizhiwuwu decoction combined with warming needle moxibustion on the basis of the control group. The course of treatment in both groups was 8 weeks. The scores of Toronto Neurological Symptom Scoring System (TCSS), neuroelectrophysiological examination results, TCM symptom scores, clinical efficacy and adverse reactions were observed before and after treatment in the two groups. Results: The TCSS scores of the two groups after treatment were significantly lower than that before treatment, and the observation group was significantly lower than that of the control group (P＜0.05); the nerve conduction velocity of the two groups after treatment were significantly higher than that before treatment, and the observation group was significantly higher than the control group (P＜0.05); the TCM symptom scores of the two groups after treatment were significantly lower than that before treatment, and the observation group was significantly lower than that of the control group (P＜0.05); the total effective rate of the observation group was 95.0%, which was significantly higher than 87.5% of the control group, the difference was statistically significant (P＜0.05); there was no obvious adverse reactions in both groups during the treatment.Conclusion: On the basis of routine treatment and mecobalamin treatment, Huangqiguizhiwuwu decoction combined with warming needle moxibustion in treating diabetic peripheral neuropathy (Qi deficiency and blood stasis syndrome) can significantly improve the clinical symptoms and signs of patients, which is conducive to the recovery of neurological function and delay the progress of disease. The clinical efficacy is definite and the safety is high. |
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