| 陈欣欣,袁敬敬.清肺化痰健脾方治疗小儿毛细支气管炎的临床研究[J].实用中西医结合临床,2021,21(6): |
| 清肺化痰健脾方治疗小儿毛细支气管炎的临床研究 |
| Clinical Study of Qingfei Huatan Jianpi Recipe in Treating Infantile Bronchiolitis |
| 投稿时间：2020-12-16 修订日期：2021-01-19 |
| DOI： |
| 中文关键词: 清肺化痰健脾方 毛细支气管炎 潮气呼吸肺功能 小儿 |
| 英文关键词: Qingfei Huatan Jianpi Recipe Bronchiolitis Tidal breathing lung function Infants |
| 基金项目: |
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| 中文摘要: |
| 目的 观察清肺化痰健脾方治疗小儿毛细支气管炎的疗效及治疗前后潮气呼吸肺功能的变化。方法 2017 年 11 月—2019 年 11月在聊城市人民医院儿科住院治疗的120例毛细支气管炎患儿，采用随机数表法按分为治疗组和对照组，每组 60 例，对照组在西医雾化干扰素、布地奈德、特布他林，吸痰等治疗基础上加用麻杏石甘汤加减治疗，治疗组在西医雾化干扰素、布地奈德、特布他林，吸痰等治疗基础上加用清肺化痰健脾方治疗，观察两组患儿临床疗效和发热、咳嗽、气喘、哮鸣音、水泡音消失时间,比较两组治疗前后潮气呼吸肺功能指标变化。结果 治疗组脱落2例，对照组3例，最终纳入治疗组58例，对照组57例。治疗组和对照组总有效率分别为94.8%和82.5%, 差异有统计学意义(P<0.05)。治疗组发热、咳嗽、气喘、哮鸣音、水泡音消失时间均明显短于对照组，P ＜ 0. 05。治疗后两组达峰时间比(TPTEF/TE)、达峰容积比（VPEF/VE）、吸呼比（Ti/Te）、每公斤体重潮气量（VT/kg）显著高于治疗前，且治疗组显著高于对照组，差异均有统计学意义(P<0.05)。结论 清肺化痰健脾方能够缩短毛细支气管炎患儿发热、咳嗽、气喘、哮鸣音、水泡音消失时间，改善肺功能，提高临床疗效。 |
| 英文摘要: |
| Objective To observe the curative effect of Qingfei Huatan Jianpi Recipe on children with bronchiolitis and the changes of tidal breathing lung function before and after treatment.Methods From November 2017 to November 2019, 120 cases of bronchiolitis inpatients in the Pediatric Department of Liaocheng People"s Hospital were divided into treatment group and control group by random number table method, 60 cases in each group,
The control group was treated with modified Maxing Shigan Decoction on the basis of Western medicine atomized interferon, budesonide, terbutaline and sputum suction, while the treatment group was treated with Qingfei Huatan Jianpi Recipe on the basis of Western medicine atomized interferon, budesonide, terbutaline and sputum suction,The clinical efficacy and disappearance time of fever, cough, asthma, wheezing, blister sound were observed in the two groups.Observe the changes in tidal breathing lung function indexes before and after treatment in both groups. Results There were 2 cases in the treatment group and 3 cases in the control group. Finally, 58 cases were included in the treatment group and 57 cases in the control group.The total effective rates of the treatment group and control group were 94.8% and 82.5%, The difference was statistically significant (P <0.05). The disappearance time of fever, cough, asthma, wheezing and blister sound in the treatment group was significantly shorter than that in the control group, P < 0.05.After treatment, the peak time ratio (TPTEF/TE), peak volume ratio (VPEF/VE), respiration ratio (Ti/Te), tidal volume per kg body weight (VT/kg) were significantly higher than before treatment, and the treatment group was significantly higher than the control group, and the differences were statistically significant (P<0.05).Conclusion Qingfei Huatan Jianpi Recipe can shorten the disappearance time of fever, cough, asthma, wheezing, blister sound in children with bronchiolitis, improve lung function, and improve clinical efficacy. |
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