| 张奇芬,杨明敏,熊燕,周海星.穴位埋针联合莫沙必利治疗糖尿病胃轻瘫的临床研究[J].实用中西医结合临床,2021,21(4): |
| 穴位埋针联合莫沙必利治疗糖尿病胃轻瘫的临床研究 |
| Clinical study of acupuncture point buried needle combined with mosapride in the treatment of diabetic gastroparesis |
| 投稿时间：2020-11-24 修订日期：2020-12-22 |
| DOI： |
| 中文关键词: 糖尿病胃轻瘫 莫沙必利 穴位埋针 胃排空 临床疗效 |
| 英文关键词: Diabetic gastroparesis Mosapride Acupuncture point buried needle Gastric emptying Clinical curative effect |
| 基金项目:江西省卫生计生委科技计划 |
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| 中文摘要: |
| 目的 观察穴位埋针联合莫沙必利治疗糖尿病胃轻瘫的临床疗效。方法 选择88例确诊为2型糖尿病胃轻瘫患者，根据随机数字表法分为观察组和对照组，每组各44例。观察组患者接受穴位埋针联合莫沙必利治疗，对照组患者接受莫沙必利治疗，疗程为8周。观察两组患者治疗前后的症状积分、临床疗效、胃半排空时间、以及空腹血糖、餐后2h血糖和糖化血红蛋白的变化，观察不良反应发生情况。结果 观察组患者治疗总有效率显著高于对照组（P＜0.01）；治疗后观察组总体症状积分显著低于对照组（P＜0.01），胃半排空时间显著短于对照组（P＜0.01）；治疗后观察组与对照组比较，空腹血糖、餐后2h血糖和糖化血红蛋白均有改善，差异有统计学意义（均P＜0.05）；两组患者均无明显不良反应发生。结论 穴位埋针联合莫沙必利治疗糖尿病胃轻瘫，临床疗效显著，可促进胃排空，改善血糖，适用于临床。 |
| 英文摘要: |
| Objective To observe the clinical effect of acupuncture point buried needle combined with mosapride in the treatment of diabetic gastroparesis. Methods Eighty-eight patients with type 2 diabetic gastroparesis were divided into group observation and group control, with 44 cases in each group according to the random number table method. Group observation were treated with acupuncture point buried needle combined with mosapride, while group control were treated with mosapride for 8 weeks. The symptom scores, clinical efficacy, gastric semi-emptying time, fasting blood glucose, 2h postprandial blood glucose and glycosylated hemoglobin were observed before and after treatment in the two groups, and the occurrence of adverse reactions were observed.Results The total effective rate of group observation was significantly higher than group control（P＜0.01）. After treatment, the overall symptom score of group observation was significantly lower than group control and the gastric semi-emptying time was significantly shorter than group control（P＜0.01）. Compared with group control, fasting blood glucose, 2h postprandial blood glucose and glycosylated hemoglobin were improved in group observation with statistically significant differences after treatment（P＜0.05）. The incidence of adverse reactions was not occurred in both group. Conclusion Acupuncture point buried needle combined with mosapride was used to treat diabetic gastroparesis,can improve clinical efficacy, promote gastric emptying, improve blood glucose, suitable for clinical. |
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