| 叶琴飞，张涛，刘蓓雯.糖尿病性胃轻瘫发病特点及对患者影响的调查研究[J].实用中西医结合临床,2020,20(6):5-7 |
| 糖尿病性胃轻瘫发病特点及对患者影响的调查研究 |
| Investigation on the Characteristics of Diabetic Gastroparesis and its Influence on Patients |
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| DOI： |
| 中文关键词: 糖尿病 胃轻瘫 血糖 |
| 英文关键词: Diabetes Gastroparesis Blood glucose |
| 基金项目:国家标准化代谢性疾病（糖尿病）管理中心项目（编号：MMC-2018） |
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| 中文摘要: |
| 目的：探讨糖尿病性胃轻瘫的发病特点及对患者的影响。方法：对2019年8月就诊的517例糖尿病患者进行横断面调查，调查对象填写人口统计学问卷、胃轻瘫主要症状指数问卷、胃轻瘫对糖尿病相关症状和血糖控制影响的调查问卷，统计胃轻瘫总体患病率，1型、2型糖尿病患者胃轻瘫患病率，分析影响2型糖尿病患者并发胃轻瘫的相关因素，胃轻瘫对患者血糖控制的影响。结果：本研究糖尿病患者胃轻瘫总体患病率为6.8%（35/517），其中1型糖尿病患者胃轻瘫患病率（13.1%，8/61）显著高于2型糖尿病患者（5.9%，27/456），差异有统计学意义（P＜0.05）。2型糖尿病患者中，使用二甲双胍控制血糖者发生胃轻瘫的比例更高[7.4%（23/310）比2.7%（4/146）]，差异有统计学意义（P＜0.05）。与2型糖尿病患者相比，1型糖尿病患者并发胃轻瘫后对血糖控制的不利影响更大，更容易导致血糖过高、低血糖发作频繁（P＜0.05）。结论：糖尿病尤其是1型糖尿病患者胃轻瘫患病率较高，二甲双胍可增加胃轻瘫发病风险或者引起胃轻瘫的相似症状，胃轻瘫对1型糖尿病患者血糖控制的不良影响较大。 |
| 英文摘要: |
| Objective: To investigate the characteristics of diabetic gastroparesis and its influence on patients. Methods: In August 2019, a cross-sectional survey was conducted on 517 diabetic patients in our hospital. All patients completed the demographic questionnaire, the main symptom index questionnaire of gastroparesis, the questionnaire on the influence of gastroparesis on diabetes related symptoms and blood glucose control. Counted the overall prevalence of gastroparesis, the prevalence of gastroparesis in type 1 and type 2 diabetic patients. The related factors influencing gastroparesis in type 2 diabetic patients and the effect of gastroparesis on blood glucose control were analyzed. Results: The overall prevalence rate of gastroparesis in diabetic patients was 6.8% (35/517), the prevalence rate of gastroparesis in type 1 diabetic patients was 13.1% among, significantly higher than that in type 2 diabetic patients (5.9%), the difference was statistically significant (P＜0.05). In type 2 diabetic patients, the incidence of gastroparesis was significantly higher in metformin users than that in non users (P＜0.05). Compared with type 2 diabetic patients, type 1 diabetic patients complicated with gastroparesis had more adverse effects on blood glucose control, and were more likely to lead to hyperglycemia and frequent hypoglycemia (P＜0.05). Conclusion: The prevalence of gastroparesis in type 1 diabetic patients is higher, and metformin can increase the risk of gastroparesis or cause similar symptoms of gastroparesis. Gastroparesis has a greater adverse effect on blood glucose control in type 1 diabetic patients. |
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