| 蔡晓晨,朱晓明.健脾利水方辅助腹腔热灌注化疗提高恶性腹水疗效的随机对照研究[J].实用中西医结合临床,2020,20(13): |
| 健脾利水方辅助腹腔热灌注化疗提高恶性腹水疗效的随机对照研究 |
| 健脾利水方辅助腹腔热灌注化疗提高恶性腹水疗效的随机对照研究 |
| 投稿时间：2020-05-15 修订日期：2020-08-30 |
| DOI： |
| 中文关键词: 健脾利水方 腹腔灌注化疗 恶性腹水 |
| 英文关键词: spleen-invigorating formula intraperitoneal chemotherapy malignant ascites |
| 基金项目: |
|
| 摘要点击次数: 536 |
| 全文下载次数: 155 |
| 中文摘要: |
| 目的：探讨健脾利水方配合腹腔热灌注化疗治疗恶性腹水临床效果。方法：以60例恶性腹水患者为对象,开始时间为2019年1月,结束时间为2019年10月,采用抽签法,随机分为参照组与研究组,每组各30例,给予参照组腹腔热灌注化疗,给予研究组健脾利水方配合腹腔热灌注化疗治疗,对比两组患者的治疗效果、腹围、尿量,进行统计学分析。结果：研究组治疗有效率高于参照组,P<0.05,表示统计学意义存在。研究组治疗后的血清CEA、CA125均低于参照组,P<0.05,表示统计学意义存在。研究组治疗后的血管紧张素II及二胺氧化酶均低于参照组,P<0.05,表示统计学意义存在。研究组治疗后的腹围小于参照组,P<0.05,表示统计学意义存在。研究组治疗后的尿量高于参照组,P<0.05,表示统计学意义存在。结论：恶性腹水使用健脾利水方配合腹腔热灌注化疗,可有效提高治疗效果,减少腹围,降低腹水量,治疗效果显著,可在临床广泛应用于推广。 |
| 英文摘要: |
| Abstract：OBJECTIVE: To investigate the clinical effect of spleen-invigorating formula combined with intraperitoneal chemotherapy in the treatment of malignant ascites. Methods： Sixty patients with malignant ascites were enrolled. The starting time was March 2017 and the end time was February 2018. They were randomly divided into reference group and study group, 30 cases in each group. Peritoneal perfusion was given to the reference group. Chemotherapy was given to the study group spleen-invigorating formula combined with intraperitoneal infusion chemotherapy. The therapeutic effects, abdominal circumference, urine volume and adverse reactions were compared between the two groups. Statistical analysis was performed. Results： The effective rate of treatment in the study group was higher than that in the control group (P < 0.05), indicating that there was statistical significance. The serum CEA, CA125 in the study group was better than that in the control group after treatment (P < 0.05), indicating that there was statistical significance. The angiotensin II and diamine oxidase in the study group were better than those in the control group (P < 0.05), indicating that there was significant difference between the two groups (P < 0.05). The score of quality of life in the study group was significantly higher than that in the control group (P < 0.05). The incidence of adverse reactions in the study group was lower than that in the control group (P < 0.05), indicating that there was statistical significance. Conclusion： The use of spleen-invigorating formula combined with intraperitoneal infusion chemotherapy can effectively improve the therapeutic effect, reduce abdominal circumference, reduce ascites, less adverse reactions, high safety and improve quality of life. It can be widely used in clinical promotion. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
