梁春云,于红娟.中药穴位贴敷治疗原发性痛经临床疗效Meta分析[J].实用中西医结合临床,2020,20(05):3-6 |
中药穴位贴敷治疗原发性痛经临床疗效Meta分析 |
Meta Analysis of Clinical Effect of Acupoint Application with Traditional Chinese Medicine in the Treatment of Primary DysmenorrheaLIANG Chun-yun1, YU Hong-juan |
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DOI: |
中文关键词: 原发性痛经 穴位贴敷 Meta分析 |
英文关键词: Primary dysmenorrhea Acupoint application Meta analysis |
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中文摘要: |
目的:系统评价中药穴位贴敷治疗原发性痛经的有效性和安全性。方法:在中国知网、万方数据库、维普全文数据库、Web of Science数据库、PubMed数据库中检索有关使用中药穴位贴敷治疗原发性痛经的临床随机对照试验文献,检索时限均为建库~2019年10月,应用RevMan5.3统计软件进行荟萃分析。结果:共纳入14篇符合条件的文献,共涉及患者1 165例,其中观察组605例,对照组560例。Meta分析结果显示:在总有效率方面,使用中药穴位敷贴敷的观察组疗效优于对照组[OR 5.15,95% CI(3.57,7.44),P<0.000 01];在中医症候评分方面,中药穴位贴敷能更好地缓解中医临床症状[MD=-2.75,95% CI(-3.47,-2.03),P<0.000 1];在疼痛评分方面,穴位贴敷相比药物治疗更能有效缓解疼痛[MD=-4.07,95% CI(-6.05,-2.09),P<0.000 1];在血浆前列腺素F2?琢、前列腺素E2水平方面,采用中药穴位贴敷治疗的观察组血浆前列腺素F2?琢[MD=-9.63,95%CI(-10.41,-8.86),P<0.000 1]和血浆前列腺素E2[MD=3.96,95% CI(1.49,6.43),P=0.002]水平相比药物治疗的对照组下降更为明显。结论:中药穴位贴敷治疗原发性痛经的临床效果较好。 |
英文摘要: |
Objective: To evaluate the efficacy and safety of acupoint application with traditional chinese medicine in the treatment of primary dysmenorrhea systematically. Methods: The literatures of clinical randomized controlled trials on the primary dysmenorrhea treated by acupoint application with traditional chinese medicine were searched in CNKI, Wanfang database, VIP full-text database, Web of Science database and PubMed database. The retrieval time was from the establishment of database to October 2019. Meta analysis was carried out by RevMan5.3 statistical software. Results: 14 Eligible literatures were included, involving 1 165 patients, there were 605 cases in the observation group and 560 cases in the control group. The meta analysis showed that: in terms of total effective rate, the therapeutic effect of the observation group was better than that of the control group [OR 5.15, 95% CI (3.57, 7.44), P<0.000 01]; in terms of TCM syndrome score, TCM acupoint application could alleviate TCM clinical symptoms better [MD=-2.75, 95% CI (-3.47, -2.03), P<0.0001]; in terms of pain visual simulation score, acupoint application was more effective in relieving pain than drug treatment [MD=-4.07, 95% CI (-6.05, -2.09), P<0.000 1]; in terms of plasma PGF2?琢 and PGE2 levels, the levels of plasma PGF2?琢 [MD=-9.63, 95% CI (-10.41, -8.86), P<0.000 1] and plasma PGE2 [MD=3.96, 95% CI (1.49, 6.43), P=0.002] in the observation group treated by acupoint application with traditional chinese medicine were significantly lower than those in the control group treated by drugs. Conclusion: The clinical effect of acupoint application with traditional chinese medicine in the treatment of primary dysmenorrhea is more effective. |
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