| 高颖,刘美芳,赵瑞婧,王丽娜,张莹莹,李娜苗,范亚莉,鱼军,邬小平,李建英.CT三维重建对孤立性肺结节良恶性诊断价值的Meta分析[J].实用中西医结合临床,2020,20(13): |
| CT三维重建对孤立性肺结节良恶性诊断价值的Meta分析 |
| A Meta-Analysis of the Value of Three-dimensional CT Reconstruction in the Diagnosis of SPN |
| 投稿时间：2020-04-03 修订日期：2020-08-28 |
| DOI： |
| 中文关键词: CT三维重建 孤立性肺结节 良恶性；Meta分析 |
| 英文关键词: CT three-dimensional reconstruction Pulmonary nodules benign and malignant Meta-analysis |
| 基金项目:1.陕西省重点研发计划项目；2.陕西省中医管理局中医药科研课题 |
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| 中文摘要: |
| 目的：通过使用Meta分析法，综合评价CT 三维重建对孤立性肺结节（SPN）良恶性的诊断价值。方法：系统搜索万方医学网、CNKI、PubMed、Medline、VIP等数据库,检索使用CT三维重建技术对孤立性肺结节诊断的相关中外文献，检索时间截至2019年10月，严格遵从Cochrane 协作网推荐的与诊断试验相关的纳入标准以筛选相关文献,提取纳入研究文献的特征信息。Meta分析采用Stata15.1SE软件进行，文献评价采用诊断实验质量评价量表QUQDAS-2。结果:共纳入9篇研究文献[1-9],共计681例患者。汇总并计算灵敏度、特异度、诊断比值比、阳性似然比及阴性似然比，同时绘制汇总受试者工作特征(SROC)曲线并计算曲线下面积(AUC)，以及95%可信区间。得到的值分别为：0.97（0.92,0.99）、0.93（0.87,0.96）、431（96,1936）、14.0（7.4,26.7）、0.03（0.01,0.09）;0.98（0.97-0.99）。结论：CT三维重建应用于孤立性肺结节良恶性的诊断，具有较高的灵敏度、特异度及准确率，是诊断孤立性肺结节良恶性一项重要的影像学方法，具有较高的诊断效能及诊断价值。 |
| 英文摘要: |
| Objective: To evaluate the diagnostic value of CT three-dimensional reconstruction for solitary pulmonary nodules (SPN) by Meta analysis. Methods: Relevant Chinese and foreign literatures on the diagnosis of solitary pulmonary nodules using CT three-dimensional reconstruction technology were searched up to October 2019. Inclusion criteria related to diagnostic trials recommended by Cochrane collaboration were strictly followed to screen relevant literatures and extract characteristic information of the included literatures. Meta analysis was conducted with Stata15.1SE software, and literature evaluation was conducted with quqda-2, a quality evaluation scale for diagnostic experiments. Results: A total of 9 studies[1-9] were included in a total of 681 patients. The sensitivity, specificity, diagnostic ratio ratio, positive likelihood ratio and negative likelihood ratio were summarized and calculated, while the summary subject"s working characteristics (SROC) curves were drawn and the area under the curve (AUC) was calculated and the 95% confidence interval was calculated. The resulting values were: 0.97 (0.92, 0.99), 0.93 (0.87, 0.96),431(96,1936),14.0(7.4,26.7), 0.03 (0.01,0.09), 0.98 (0.97-0.99).Conclusion:CT three-dimensional reconstruction is an important imaging method for the diagnosis of benign and malignant solitary pulmonary nodules with high sensitivity, specificity and accuracy. |
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